Autosomal dominant syndrome with strokelike episodes and leukoencephalopathy.

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Autosomal dominant syndrome with strokelike episodes and leukoencephalopathy.

BACKGROUND AND PURPOSE We conducted a prospective survey of a family presenting a new syndrome characterized mainly by recurrent strokelike episodes and neuroimaging evidence of leukoencephalopathy. SUMMARY OF REPORT Forty-five members of a single family were studied clinically and with magnetic resonance imaging. Nine had strokelike episodes, including transient ischemic attacks, and minor o...

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Background and Purpose: The precise mechanism of neurological symptoms with mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes (MELAS) is still controversial. We investigated the correlation between strokelike episodes and cerebral blood flow in two patients with MELAS and discuss the pathogenesis of strokelike episodes with MELAS. Summary of Report: Cerebral dynam...

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ژورنال

عنوان ژورنال: Stroke

سال: 1991

ISSN: 0039-2499,1524-4628

DOI: 10.1161/01.str.22.10.1297